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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEDD All Species: 27.27
Human Site: S238 Identified Species: 75
UniProt: O75618 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75618 NP_001034800.1 318 36794 S238 Q A N T I L K S R D L G S I I
Chimpanzee Pan troglodytes XP_001172953 348 40386 S268 Q A N T I L K S R D L G S I I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545766 318 36786 S238 Q A N T I L K S R D L G S I I
Cat Felis silvestris
Mouse Mus musculus Q9Z1L3 318 36787 S238 Q A N T I L K S R D L G S I I
Rat Rattus norvegicus Q9Z2K0 318 36829 S238 Q A N T I L K S R D L G S I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520660 116 12937 Q52 G V Q S R R P Q P L A R Q L D
Chicken Gallus gallus XP_423146 318 36729 S238 Q A N T I L K S R D L G S I I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002639 404 44870 S313 Q A N T I L K S R D L G S I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198205 159 18300 F95 S I V C D I K F S E L T Y L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 N.A. 99.6 N.A. 98.7 98.4 N.A. 25.1 88.6 N.A. 59.9 N.A. N.A. N.A. N.A. 36.4
Protein Similarity: 100 91.3 N.A. 99.6 N.A. 99 98.7 N.A. 28.9 93.4 N.A. 67.3 N.A. N.A. N.A. N.A. 42.7
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 0 100 N.A. 100 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 13.3 100 N.A. 100 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 78 0 0 0 0 0 0 0 0 12 0 0 0 0 % A
% Cys: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 12 0 0 0 0 78 0 0 0 0 23 % D
% Glu: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % F
% Gly: 12 0 0 0 0 0 0 0 0 0 0 78 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 78 12 0 0 0 0 0 0 0 78 78 % I
% Lys: 0 0 0 0 0 0 89 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 78 0 0 0 12 89 0 0 23 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 0 % P
% Gln: 78 0 12 0 0 0 0 12 0 0 0 0 12 0 0 % Q
% Arg: 0 0 0 0 12 12 0 0 78 0 0 12 0 0 0 % R
% Ser: 12 0 0 12 0 0 0 78 12 0 0 0 78 0 0 % S
% Thr: 0 0 0 78 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _